Who pioneered vaccination with the smallpox vaccine? By Rabia Anum π Source Historic Inventions Knowledge Base β Fact Checked π Difficulty Medium π Last Updated 13 Aug 2026 A. Penicillin B. Anesthesia C. Edward Jenner D. Antiseptic Check Answer π‘ Explanation: Edward Jenner developed the first vaccine (for smallpox) in 1796. π Topics: Historic Inventions Inventions and Discoveries π― Exams: CSS GEN NTS PMS