What is the largest single organ of the human body, serving as a protective barrier against the external environment? A. The Lungs B. The Liver C. The Skin D. The Brain Check Answer 💡 Explanation: The skin, which constitutes the integumentary system, is considered the largest organ in the human body both in terms of surface area and weight. 📚 Topics: Biology Science 💡 Found this helpful? Share with friends! Share Tweet WhatsApp Share